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Alexander Ratushny

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I am currently a Senior Scientist at Seattle Biomed and an Affiliate Scientist at Institute for Systems Biology in Seattle, USA.

My CV.

My principal area of research is mathematical modeling of dynamical biological systems.

 

News

September 2014

Systems cell biology. J Cell Biol. 2014 Sep 15;206(6):695-706

March 2014

Nuclear pore complex evolution: A trypanosome Mlp analog functions in chromosomal segregation but lacks transcriptional barrier activity. Mol Biol Cell. 2014 Mar 5

February 2014

An evolutionarily conserved RNase-based mechanism for repression of transcriptional positive autoregulation, Mol Microbiology. 2014 Feb 24. doi: 10.1111/mmi.12564

November 2013

Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity, Nature. 2013 Nov 27. doi: 10.1038/nature12862

October 2013

Molecular mechanisms of system responses to novel stimuli are predictable from public data, Nucleic Acids Res. 2013 Oct 31

January 2013

Metallochaperones regulate intracellular Copper levels, PLoS Comput Biol 9(1): e1002880. doi:10.1371/journal.pcbi.1002880

January 2013

Member of the Editorial Board of the IET Systems Biology Journal

September 2012

A FOXO3-IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses, Nature. 2012 Sep 16. doi: 10.1038/nature11428

July 2012

A FOXO3-IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses, Nature, accepted

April 2012

Asymmetric positive feedback loops reliably control biological responses, Mol Syst Biol. 2012 Apr 24; 8:577

March 2012

NUP-1 is a large coiled-coil nucleoskeletal protein in trypanosomes with

lamina-like functions, PLoS Biol. 2012 Mar;10(3):e1001287

March 2012

Asymmetric positive feedback loops reliably control biological responses, Molecular Systems Biology, accepted

January 2012

NUP-1 is a large coiled-coil nucleoskeletal protein in trypanosomes with

lamina-like functions, PLoS Biology, accepted

September 2011

Mathematical modeling of biomolecular network dynamics, Methods Mol Biol. 2011;781:337-52

June 2011

PLoS Computational Biology cover

June 2011

Trade-off between Responsiveness and Noise Suppression in Biomolecular System Responses to Environmental Cues, PLoS Comput Biol 7(6): e1002091

April 2011

Highlight at Celebrating Science - A Family Science Project